Last OEM version of the Scrambler Therapy® Technology device. In production since 2021 (fully made in Italy). To optimize product quality and comply in advance with the constantly evolving international requirements for medical devices, production was moved from Korea (previous generations MC-5A) to Italy. On this occasion the new device was improved in many parts, such as mechanics, design, connectors, EMC, and quality control. The power supply system now also accepts 110-120V. The new Scrambler Therapy® ST-5A device replaces the previous model, MC-5A, and it is the only Scrambler Therapy® device on the market.

The scientific literature indexed and published in peer-reviewed scientific journals, based exclusively on this technology, shows several clinical studies on:

- Symptomatic relief of chronic opioid-resistant pain.

- Symptomatic relief of chronic neuropathic and oncological pain.

In general, this device in the clinical studies is indicated for forms of severe chronic pain, in particular that which does not respond to other pharmacological and non-pharmacological treatments, including opioids. It is currently the only Scrambler Therapy® device in production.
International distribution (including in the U.S.) is entrusted exclusively to Delta International Services & Logistics.

It is the second OEM version of the device (2014-2019). Aesthetically there are no variations with the previous version, but the OEM artificial neuron core support technology external has undergone significant improvements in its reliability.

This second OEM version is recognizable by the 510(k) # K142666 and CE marking 0476. This device production was interrupted in 2020.

The first industrialized OEM version (the hardware and software project core of artificial neurons used in clinical trials cannot be modified) known in the U.S. also has the alternative trade name of “Calmare,” sometimes also present on the device with a self-adhesive label.

This device was manufactured in 2008, recognizable by the 510(k) # K081255 and the CE 0470 marking. This device production was interrupted in 2013.

The prototype was used for clinical studies in Italy (2297 cases of various types of serious neuropathic pain that were resistant to medications and/or electro-analgesia) until 2007. Software core of artificial neurons and the ST stable technology.